OncoMouse

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Definition

OncoMouse is both a noun and a trademark. It is a term used to describe a transgenic mouse carrying an activated human cancer gene, used in laboratory experiments.[1] OncoMouse also the first patented animal. Two patents were awarded to Harvard College that covered methods for providing a cell culture from a transgenic non-human animal.[2]

Philip Leder and Timothy A Stewart[3] of Harvard University designed the mouse to carry an activated oncogene, a specific gene that significantly increases the mouse’s susceptibility to cancer. This makes suitable for cancer research. The rights to the invention are owned by DuPont. "OncoMouse" is a registered trademark.[4]

References

  1. New Oxford American Dictionary
  2. U.S. Patent 5,087,571; filed Mar 22, 1988, issued Feb 11, 1992, expired Feb 11, 2009) and testing methods using transgenic mice expressing an oncogene, U.S. Patent 5,925,803; filed Sep 19, 1991, issued Jul 20, 1999, expires July 20, 2016.
  3. European Patent Register entry for European patent no. 0169672, under "Inventor(s)". Consulted on February 22, 2008.
  4. Trademark: USPTO serial number 75797027